Synthesis of (3R,5R)-harzialactone a and its (3R,5S)-isomer

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Abstract

The total synthesis of (3R,5R)-harzialactone A (1) and its (3R,5S)-isomer (2) is described. Epoxide opening with thioacetal and diastereoselective reductions are used as key reactions. © 2010 Sabitha et al.

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Sabitha, G., Srinivas, R., Das, S. K., & Yadav, J. S. (2010). Synthesis of (3R,5R)-harzialactone a and its (3R,5S)-isomer. Beilstein Journal of Organic Chemistry, 6. https://doi.org/10.3762/bjoc.6.8

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