Structure and biology of self lipid antigens

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Abstract

Self lipid antigens induce selection and expansion of autoreactive T cells which have a role in immunoregulation and disease pathogenesis. Here we review the important biological rules which determine lipid immunogenicity. The impact of lipid structure, synthesis, traffic, membrane distribution and CD1 loading are discussed. © Springer-Verlag 2007.

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De Libero, G., & Mori, L. (2007). Structure and biology of self lipid antigens. Current Topics in Microbiology and Immunology. Springer Verlag. https://doi.org/10.1007/978-3-540-69511-0_3

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