Abstract
Two active metabolites of ML-236B, 4b,6α-dihydroxy ML-236B (M3, 2), and 3b-hydroxy ML-236B (M4, 3), were isolated from the urine of ML-236B-treated dogs. The structures of M3 and M4 were elucidated on the basis of spectral data and confirmed by X-ray analysis. © 1986, The Pharmaceutical Society of Japan. All rights reserved.
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Terahara, A., Nishigaki, T., Kinoshita, T., & Tamura, C. (1986). Structure Elucidation of the Bioactive Metabolites of ML-236B (Mevastatin) Isolated from Dog Urine. Chemical and Pharmaceutical Bulletin, 34(4), 1459–1467. https://doi.org/10.1248/cpb.34.1459
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