An electrophysiological method for quantifying neuropathic pain behaviors in rats: Measurement of hindlimb withdrawal EMG magnitude

Abstract

In behavior methods to quantify neuropathic pain, visual observations of limb-withdrawal reflexes to stimuli are not always clear-cut, so this method is partly subjective. Our current data suggest that measurement of electrophysiological EMG magnitudes enables more reliable and objective assessment for quantifying nocifensive behaviors related to neuropathic pain. © 2009 The Physiological Society of Japan and Springer.