Treatment protocol of coronavirus infection (COVID-19) in children with chronic somatic diseases

Abstract

The article summarizes the clinical recommendations for the diagnosis and treatment of children with coronavirus infection COVID019, which occurs against a background of various chronic somatic diseases. This protocol is based on the materials of many international reference documents, as well as the latest Ukrainian protocol for the detection and treatment of coronavirus infection COVID019 (Order No. 1227 of 05.20.2020). Aspects of the classification of severi0 ty and risk factors for the severe course of the disease are reflected, which include background somatic diseases requiring an individualized approach to treat0 ment. The diagnostic criteria for this infection are characterized, as well as the differences in the clinical symptoms of COVID019 in children and the clinical manifestations in adults. Separately, data are presented on the complication of childhood COVID019 infection, a multisystemic inflammatory syndrome. The peculiarity of this protocol is recommendations for the management of children with COVID019 infection, which occurs against a background of diseases of the cardiovascular system (congenital heart defects, pulmonary hypertension, cardiac arrhythmias and conduction disorders, etc.), respiratory diseases (bronchial asthma and bronchopulmonary dysplasia), rheumatic (juvenile arthritis, connective tissue diseases and systemic vasculitis with lung damage, vari0 ants of diseases requiring constant glucocorticoid therapy or occurring in the presence of diabetes mellitus) and other autoimmune diseases (autoimmune hepatitis, glomerulonephritis, especially with chronic liver or kidney failure). Recommendations are also given for the management of children with COVID019 concurrently with diseases of the kidneys and urinary system, endocrine diseases (diabetes mellitus type I, disorders of the thyroid and adrenal glands), onco0 logical and hematological diseases, including the immunosuppression states.