Chromosome Segregation: Centromeres Get Bent

Abstract

Work over the last several decades has shown that kinetochores play an active part in chromosome segregation, while the chromatin and, more to the point, the DNA have gathered little attention. In two intriguing papers, the Bloom and Khodjakov groups show that intercentromeric chromatin plays a much more active part in chromosome segregation than previously suspected. © 2008 Elsevier Ltd. All rights reserved.