A fast preparative method for detection of recombinant erythropoietin in blood samples

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Abstract

Isoelectric focusing is the basis of anti-doping control of recombinant erythropoietin in urine. A convenient preparative method is proposed for screening of Continuous Erythropoietin Receptor Activator (CERA) and Darbepoetin alfa in serum or plasma. This method makes isoelectric focusing as easy to use in blood as in urine. In comparison with urine, EPO analyses in blood appear beneficial in terms of sensitivity, stability during physical exercise, and prevention of sample adulteration at collection. Copyright © 2010 John Wiley & Sons, Ltd.

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Lasne, F., Martin, L., & Martin, J. A. (2010). A fast preparative method for detection of recombinant erythropoietin in blood samples. Drug Testing and Analysis. John Wiley and Sons Ltd. https://doi.org/10.1002/dta.171

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