Anaphylaxis caused by anti-cremophor el igg sts antibodies in a case of reaction to althesin

Abstract

The action of cremophor EL, the solubilizing agent of Althesin in a case of anaphylactic reaction which occurred during the induction of anaesthesia has been demonstrated using the Prausnitz-Küstner (P-K) test 10 weeks later. This test was positive at 2 h, with the heated serum and cremophor, proving the presence of allergic IgG STS antibodies. © 1983 The Macmillan Press Ltd.