Effect of lactobacillus pentosus S-PT84 ingestion on IFN-A production from plasmacytoid dendritic cells by virus stimulation

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Abstract

We investigated the effect of ingesting Lactobacillus pentosus S-PT84 on the interferon-a (IFN-a) production from splenocytes and plasmacytoid dendritic cells by virus stimulation. IFN-a production by the Lactobacillus pentosus S-PT84 ingestion group was significantly greater under the virus-infected condition than that by the control group. Lactobacillus pentosus S-PT84 could enhance the production of IFN-a which is known as an important cytokine for preventing virus infection. It may therefore become a prophylactic tool against such virus infection.

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Izumo, T., Maekawa, T., Ida, M., Kishi, A., Akatani, K., Kitagawa, Y., & Kiso, Y. (2011). Effect of lactobacillus pentosus S-PT84 ingestion on IFN-A production from plasmacytoid dendritic cells by virus stimulation. Bioscience, Biotechnology and Biochemistry, 75(2), 370–372. https://doi.org/10.1271/bbb.100696

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