Effects of probiotics on haematology and biochemical parameters in mice

Abstract

Probiotic organisms are live microorganisms thought to be beneficial to the host. To know the effect of probiotic supplemented food on haemato-biochemical parameters in mice, a total of 20 two-month-old Swiss Albino mice were randomly divided into four equal groups. Group A was control, fed commercial mouse pellets, and others were treated with 5 g (group B), 10 g (group C) and 20 g (group D) probiotics (curd), respectively, in mouse pellets for 45 days. Total erythrocyte count and haemoglobin concentration were significantly (P<0.01) higher in treated group than in controls. Total serum cholesterol, triglyceride, high density lipoprotein and low density lipoprotein values decreased significantly (P<0.01) in treated groups. Serum uric acid value was significantly higher (P<0.01) in treated groups. It is suggested that probiotics help improve haematology and lipid profile but not kidney function. DOI: http://dx.doi.org/10.3329/bvet.v30i1.16281 Bangl. vet. 2013. Vol. 30, No. 1, 20-24