Malondialdehyde and homocysteine levels in patients with unexplained female infertility

Abstract

Objectives: To assess association in between malondialdehyde and homocysteine in females with unexplained infertility. Methods: A case control study. Setting: Hospital based. Patients: Fifty females diagnosed with unexplained infertility were matched with fifty normal healthy controls. Intervention: Blood samples for malondialdehyde, a lipid peroxidation product and homocysteine measurements. Results: Our study suggests that females with unexplained infertility have increase in malondialdehyde along with hyperhomocysteinemia when compared with normal healthy controls. Conclusion: Determination of levels of malondialdehyde and homocysteine should be incorporated as one of the factors for ascertaining the cause of female unexplained infertility.