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Protective effect of monoclonal antibodies on lethal mouse hepatitis virus infection in mice

  • Nakanaga K
  • Yamanouchi K
  • Fujiwara K
Journal of Virology (1986) 59(1) 168-171
DOI: 10.1128/jvi.59.1.168-171.1986
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Abstract

Neutralizing and nonneutralizing monoclonal antibodies to the peplomer glycoprotein and nucleocapsid protein of a mouse hepatitis virus (MHV), MHV-NuU, protected mice against lethal MHV-2 challenge. Histopathologically, livers of mice receiving protective antibodies showed some focal necrotic lesions with remarkable cellular infiltration instead of fulminant hepatitis caused by MHV-2.

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APA

Nakanaga, K., Yamanouchi, K., & Fujiwara, K. (1986). Protective effect of monoclonal antibodies on lethal mouse hepatitis virus infection in mice. Journal of Virology, 59(1), 168–171. https://doi.org/10.1128/jvi.59.1.168-171.1986

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