Charting a novel path towards Ebola virus disease preparedness: Considerations for preventive vaccination

Abstract

In June 2024, Gavi, the Vaccine Alliance, launched a preventive vaccination program against Ebola virus disease (EVD). This marks a historic shift in the management of EVD, allowing at-risk countries across sub-Saharan Africa to request support in implementing preventive vaccination campaigns. This perspective piece shares considerations that can inform how countries approach preventive EVD vaccination and potential unintended consequences. It also provides insights into strategies for vaccines against other epidemic-prone pathogens.