Synthesis, Characterization and Antimicrobial activity of 2- Amino-1,3-benzothiazole, Schiff bases and Azo dyes of 2-Amino- 1,3-benzothiazole.

Abstract

2-Amino-1,3-benzothiazole was synthesized and schiff bases were prepared by reacting a series of aromatic aldehydes with 2-amino-1,3-benzothiazole to form a number of potentially biologically active compounds. Azo dyes of 2-amino-1,3-benzothiazole were synthesized by reacting various aromatic amines , substituted amines and phenols. The structures of 2-amino-1,3-benzothiazole, Schiff bases and azo dyes were confirmed by using FT-IR, 1 H-NMR, Mass, UV, spectroscopic technique. The dyeing ability of azo dyes was checked by applying azo dyes on various fabrics. The tiltle compounds were also tested against representatives of gram-positive and gram-negative bacteria by agar diffusion method. Ampicillin was used as positive control.