Introduction Approximately 5-10% of global cancer has a genetic base. Nowadays it is possible to identify those who have a genetic predisposition for some cancers, so they can be treated in short term. Objectives Evaluate how useful is prophylactic surgery on hereditary Medullary Thyroid Cancer. Materials and methods This investigation is a literature review of different research papers from electronic databases such as Scientific Electronic Library Online (SciELO), MedLine-PubMed and UpToDate. The research was made with clinical queries and MeSH terms, specially focused on hereditary Medullary Thyroid Cancer. Results This research shows that prophylactic Thyroidectomy with cervical lymph node resection is the only effective and curative treatment for hereditary Medullary Thyroid Cancer. Conclusions Prophylactic surgery has proof an important role decreasing the risk on Hereditary Thyroid cancer Syndrome and in RET carriers surgery is considered a must.
Fuenzalida R., R., Vial L., I., Rojas O., V., Pizarro C., F., Puebla R., V., & Vial L., G. (2017, May 1). Cirugía profiláctica en cáncer medular de tiroides hereditario. Revista Chilena de Cirugia. Elsevier Espana S.L. https://doi.org/10.1016/j.rchic.2016.11.002