The Synthesis of 3-Arylquinolines from o-Nitrobenzaldehydes and β-Nitrostyrenes via an Iron-Promoted Reductive Cyclization

Abstract

An iron-mediated one-pot synthesis of 3-arylquinolines from o-nitrobenzaldehydes and β-nitrostyrenes has been developed. Iron acted as dual roles to trigger the reduction of o-nitrobenzaldehydes and reduction hydrolysis of β-nitrostyrenes, which subsequently integrated to quinoline derivatives.