Open-source platform for the analysis of liquid chromatography-mass spectrometry (LC-MS) data

Abstract

The analysis of protein mixtures by liquid chromatography-mass spectrometry (LC-MS) requires tools for viewing and navigating LC-MS data, locating peptides in LC-MS data, and eliminating low-quality peptides, msInspect, an open source platform, can carry out these steps for single experiments and can align and normalize peptide features in comparative studies with multiple LC-MS runs. In addition, msInspect can analyze quantitative studies with and without isotopic labels to generate peptide arrays. © Humana Press.