Regulation of tartary buckwheat-resistant starch on intestinal microflora in mice fed with high-fat diet

Abstract

Resistant starch (RS) is closely related to the composition of intestinal flora. Based on many studies on the physiological functions of probiotics and short-chain fatty acids (SCFAs), it is possible that RS can improve the intestinal health of the host. Therefore, we speculated that tartary buckwheat-resistant starch (TBRS) can also regulate the intestinal flora disorder caused by high-fat diet. We randomly divided 36 SPF C57BL/6J mice into low-fat diet, high-fat diet (HF-CS), high-fat diet supplemented with TBRS (HF-BRS), and high-fat diet supplemented with corn-resistant starch (HF-CRS). We analyzed the diversity and richness of gut microbiota based on PCR and Illumina high-throughput sequencing technology. In community abundance, the HF-BRS group was significantly higher than the other three groups (p