AAA+ ATPase protein machines use the power obtained from ATP hydrolysis to remodel macromolecular assemblies in the cell. Recent work in Escherichia coli on the ClpX AAA+ protein reveals fundamental mechanical principles that underlie ClpX motor function.
Ades, S. E. (2006, January 24). AAA+ molecular machines: Firing on all cylinders. Current Biology. https://doi.org/10.1016/j.cub.2006.01.005