Pengaruh Kehamilan Terhadap Frekuensi Kekambuhan Asma Pada Ibu Hamil Trimester I, II Dan III Dengan Riwayat Asma Di Kota Malang

Abstract

In Indonesia, the prevalence of asthma ranged between 5%-6% of the population. With the prevalence of asthma in pregnancy ranged between 3.7%-4%, the cellular immune deficiencies can be found in pregnancy. In asthmatic pregnancy with rising of IgE and no changes IgE have a tendency of worsening asthma exacerbations during pregnancy. The Aim of this research is to prove the influence of pregnancy on relapse frequency of asthma in trimester I, II and III pregnant women with asthma. This research type is the comparative study. Populations in this study were all pregnant woman with asthma. The sample was selected in accordance with the study inclusion criteria and the sampling technique was done by incidental sampling. The results shows the statistic of Friedman test is p=0. 03. It is smaller than the=0.05. It means there is a significant correlation between relapse frequency of asthma and the pregnant women in trimester I, II and III.The value of the correlation is r=0,1. It shows that the strength of correlation is very weak, and there is positive correlation. R 2 =3,6% shows that pregnancy have 3,6% effect on the asthma relapse frequency at pregnancy. Physical changes, emotional and biochemical relapse during pregnancy cause asthma in pregnancy, especially in the third trimester of emotion. Changing of immunity in pregnancy, particularly the decline in cell-mediated immunity, allegedly as predisposing to infection in people with asthma could lead to a worsening of asthma. The conclusion of the research is that there is asthma relapse frequency difference between the trimester I, II and III of pregnancy, in which the highest frequency of relapse is in the third trimester. The suggestion of the research is that the strict monitoring and correct treatment in pregnant women with asthma by Ante Natal Care (ANC) must be done regularly .