Adverse Health effects Associated with Shift Work

Abstract

Shift work is the integral part of many occupations. WHO listed shift wok that involves disruption of circadian disruption as a probablecarcinogen? Shift work increases the risk for the development of many health disorders e.g. Sleepdisruption, risk of diabetes,alteration of circadian rhythm,cardiovascular disease, metabolicdisorders, increased risk of breast cancer, stress, reproductive disorders and work place safety and errors. Shiftwork has no adverse effect on mortality. Melatonin may increase sleep length. Modanifil and MR-Modanifil are useful to improve alertness, reduce sleepiness in shift workers. The license for Modanifil was withdrawn because the benefits did not out way the side effects. Better management of shift work. Frequent breaks and 8-10 hour shifts instead of 12 hour can also minimize fatigue and help to mitigate the negative health effects of shift work.