Evaluation the effect of antibiotics and probiotics supplementation in feed on broilers chicken immunity status

Abstract

Antibiotics and probiotics play important roles in the feed of broiler chickens. Antibiotics are commonly used in poultry production to prevent and treat bacterial infections, promote growth, and improve feed efficiency. Evaluation of antibiotic and Probiotic effects on growth performance, cecal microbiota, and immune response of broilers were studied. 150 one-day-old male chickens were allocated to five treatments (six replicates of 5 birds per treatment). The chicken challenged was infected with Salmonella Pullorum per os twice at 7 and 8 day-aged.The results of this study suggest that the addition of Brevibacillus laterosporus texasporus culture at a dosage of 100 mg/kg in feed can improve the growth performance of broiler chickens that have been challenged by Salmonella infection. Considering the development of immune organs in broilers, the shift away from AGPs toward probiotics is evident. Probiotics, by fostering a healthier gut environment and supporting gut-associated immune responses, offer a more targeted and sustainable approach to enhancing immune organ development.