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Evaluating the Presence of Replication-Competent Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) From Nursing Home Residents With Persistently Positive Reverse Transcription Polymerase Chain Reaction (RT-PCR) Results

Clinical Infectious Diseases (2022) 74(3) 525-528
DOI: 10.1093/cid/ciab436
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Abstract

Replication-competent virus has not been detected in individuals with mild to moderate coronavirus disease 2019 (COVID-19) more than 10 days after symptom onset. It is unknown whether these findings apply to nursing home residents. Of 273 specimens collected from nursing home residents >10 days from the initial positive test, none were culture positive.

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Lutgring, J. D., Tobolowsky, F. A., Hatfield, K. M., Lehnertz, N. B., Sullivan, M. M., Martin, K. G., … Jernigan, J. A. (2022). Evaluating the Presence of Replication-Competent Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) From Nursing Home Residents With Persistently Positive Reverse Transcription Polymerase Chain Reaction (RT-PCR) Results. Clinical Infectious Diseases, 74(3), 525–528. https://doi.org/10.1093/cid/ciab436

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