Diprenylated Indole Alkaloids from Fruits of Hexalobus monopetalus

Abstract

New hexalobine type alkaloid, 5-(2″,3″-epoxy-3″-methylbutyl)-3-(3′-hydroxy-3′-methyl-1′-acetyloxy-but-2′-yl)indole (1) alongside the known hexalobines 3-(2′,3′-dihydroxy-3′-methylbutyl)-5-(3″-methylcrotonoyl) indole (2), 3,5-hexalobine C (3) and 3,5-hexalobine D (4) were isolated from fruits of Hexalobus monopetalus. Compounds 3 and 4 exhibited antifungal activity against Candida albicans.