Structure of Unliganded GRP94, the Endoplasmic Reticulum Hsp90

  • Dollins D
  • Immormino R
  • Gewirth D
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Abstract

... conformational changes are observed in the isolated N-domain of GRP94 , however, clearly distinguishes the GRP94 system from that of Hsp90 . ... 7. Model for GRP94 conformational changes in response to ligand. ... Rdc and Gdm denote radicicol and geldanamycin , respectively. ...

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Dollins, D. E., Immormino, R. M., & Gewirth, D. T. (2005). Structure of Unliganded GRP94, the Endoplasmic Reticulum Hsp90. Journal of Biological Chemistry, 280(34), 30438–30447. https://doi.org/10.1074/jbc.m503761200

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