A Case of Primary Systemic Amyloidosis

Abstract

A 71-year-old Japanese man with primary systemic amyloidosis with various cutaneous manifestations died by cardiac insufficiency. Autopsy revealed massive deposition of amyloid in all organs and tissues. In the skin, amyloid material was seen iti the dermis, particularly around the small vessels, sebaceous glands, hair follicles and beneath tile epidermis. The deposit did not lose Congo red affinity after exposure to potassium permanganate. © 1985, Western Division of Japanese Dermatological Association. All rights reserved.