Congenital diaphragmatic hernia: An overview of the etiology and current management

Abstract

Aim: To review provide an overview of the etiology and current strategies in the management of congenital diaphragmatic hernia (CDH). Methods: We did a comprehensive review of research trends, evidence based studies and epidemiologic studies. Results: CDH is a life-threatening pathology in infants, and a major cause of death due to the pulmonary hypoplasia and pulmonary hypertension. There is much research related to elucidating the etiology of CDH and developing management strategies to improve the outcomes in these infants. Conclusion: An early diagnosis with increased understanding of this disease is a crucial factor for a timely approach to managing the critically ill infant, and to offer the potential for improved outcomes and substantial reductions in morbidity. © 2008 Foundation Acta Pædiatrica/Acta Pædiatrica.