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Homogeneous chiral nickel-catalyzed asymmetric hydrogenation of substituted aromatic α-aminoketone hydrochlorides through dynamic kinetic resolution

ChemCatChem (2009) 1(2) 237-240
DOI: 10.1002/cctc.200900084
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Abstract

Vive la résolution: Homogeneous chiral nickel complexes catalyze the asymmetric hydrogenation of substituted aromatic α-aminoketone hydrochlorides through dynamic kinetic resolution to afford medicinally important β-aminoalcohols with excellent diastereo- and enantioselectivities. © 2009 Wiley-VCH Verlag GmbH& Co. KGaA, Weinheim.

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Hibino, T., Makino, K., Sugiyama, T., & Hamada, Y. (2009). Homogeneous chiral nickel-catalyzed asymmetric hydrogenation of substituted aromatic α-aminoketone hydrochlorides through dynamic kinetic resolution. ChemCatChem, 1(2), 237–240. https://doi.org/10.1002/cctc.200900084

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