A new photoclick reaction strategy: Photo-induced catalysis of the thiol-Michael addition via a caged primary amine

Abstract

The utilization of 2-(2-nitrophenyl)propyloxycarbonyl (NPPOC) as a photolabile primary amine cage enables the thiol-Michael ‘click’ reaction to be photo-triggered. The photolabile amine exhibits efficient catalytic activity upon UV irradiation and is shown to initiate the photopolymerization of tetrathiol and diacrylate comonomers via Michael addition. © 2013 The Royal Society of Chemistry.