Summary: The decline in CD4+ T cell function with aging contributes to reduced vaccine efficacy. In this commentary, we discuss the factors leading to age-related changes in T cell function and propose how they may be overcome to enhance vaccine efficacy for the elderly. © 2006 Elsevier Inc. All rights reserved.
Haynes, L., & Swain, S. L. (2006). Why Aging T Cells Fail: Implications for Vaccination. Immunity. Cell Press. https://doi.org/10.1016/j.immuni.2006.06.003