Understanding the origins of insulin-producing beta cells of the pancreas could lead to new treatments for diabetes. Collombat et al. (2009) now show that in response to injury, a population of pancreatic progenitor cells can give rise to glucagon-expressing alpha cells that then transdifferentiate into beta cells. © 2009 Elsevier Inc. All rights reserved.
Liu, Z., & Habener, J. F. (2009, August 7). Alpha Cells Beget Beta Cells. Cell. https://doi.org/10.1016/j.cell.2009.07.022