Anti-diabetic and anti-oxidant status of Loranthus pulverulentus obtained from two different hosts

0Citations
Citations of this article
5Readers
Mendeley users who have this article in their library.

Abstract

Leaves of Loranthus pulverulentus have been used ethnically in Pakistan for controlling blood glucose levels. The present study was designed to investigate the anti-diabetic and anti-oxidant potential of the methanolic extracted fractions of L. pulverulentus obtained from two different hosts’ viz. Dalbergia sissoo and Populus nigra. The acute study demonstrated that L. pulverulentus (D. sissoo) leaves possess significant blood glucose lowering effect whereas L. pulverulentus (P. nigra) was didn’t significantly decreased blood glucose levels. The n-butanol fraction of L. pulverulentus (D. sissoo) also significantly increased in vivo total anti-oxidant activity on eighth day after treatment and blood glucose levels were significantly reduced (%46.7) when compared to the control diabetic group (%↑198.1) and metformin treated group (%↓25.9). Leaves of L. pulverulentus (D. sissoo) have good margin of safety as therapeutic index is 3.5. This study provides scientific evidence that leaves of L. pulverulentus (D. sissoo) possess potential anti-diabetic activity whereas L. pulverulentus (P. nigra) was not found effective in diabetic illness.

Cite

CITATION STYLE

APA

Kamran, S. H., Ahmad, M., Shahwar, D., & Ajaib, M. (2016). Anti-diabetic and anti-oxidant status of Loranthus pulverulentus obtained from two different hosts. Bangladesh Journal of Pharmacology, 11(1), 181–189. https://doi.org/10.3329/bjp.v11i1.24056

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free