Antioxidant activities of dithiol alpha-lipoic acid

  • Islam M
Citations of this article
Mendeley users who have this article in their library.


Alpha-lipoic acid, a dithiol compound derived from octanoic acid, which acts as a coenzyme for several redox reactions in almost all the tissue of the body. It retains its protective functions in both oxidized and reduced forms. Alpha-lipoic acid reduces oxidative stress by redox generation of other antioxidants such as vitamin C, E and increasing the intracellular glutathione. Exogenous alpha-lipoic acid has been shown to increase ATP production due to its role in the oxidation of pyruvate and alpha-ketoglutarate in the mitochondria. Alpha-lipoic acid administration has been shown to be effective in preventing pathology in various experimental models in which reactive oxygen species have been implicated. Key words: Antioxidant, free radical, alpha-lipoic acid   DOI: 10.3329/bjms.v8i3.3982 Bangladesh Journal of Medical Sciences Vol.8(3) 2009 p46-51




Islam, M. T. (1970). Antioxidant activities of dithiol alpha-lipoic acid. Bangladesh Journal of Medical Science, 8(3), 46–51.

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free