The aortic root in supravalvular aortic stenosis: The potential surgical relevance of morphologic findings

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Abstract

Objective: We aimed to elucidate the structural basis of supravalvular aortic stenosis in the context of its surgical repair. Methods: We examined retrospectively the angiograms and echocardiograms of 37 patients and compared them with those of control groups. Additionally, we studied 8 pathologic specimens. Results: Partial adhesion of the leaflets to the stenosing ridge was observed in 54% of the cases and the leaflets were thickened and less mobile in 30%. Forty-five percent of the angiograms showed evidence of coronary orificial stenosis. The sinuses of Valsalva were significantly enlarged in 75% of the cases. Changes in dimensions of the aortic root were demonstrated more clearly by angiography than by echocardiography. In all anatomic specimens, a marked redundancy of the leaflets was observed and quantified. Conclusions: Our data demonstrate that the entire valvular apparatus is always affected by the so-called supravalvular stenosis. Anatomic restoration of the aortic root should ideally take into account all of the deformed components by enlarging all three sinuses of Valsalva at the sinotubular junction.

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Stamm, C., Li, J., Siew Yen Ho, Redington, A. N., & Anderson, R. H. (1997). The aortic root in supravalvular aortic stenosis: The potential surgical relevance of morphologic findings. Journal of Thoracic and Cardiovascular Surgery, 114(1), 16–24. https://doi.org/10.1016/S0022-5223(97)70112-0

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