This was a retrospective audit assessing vancomycin dosing of 60 mg/kg/day in the attainment of therapeutic concentrations between 10–20 mcg/mL among 56 pediatric oncology patients. Twelve patients (21%) achieved therapeutic concentrations of 10–20 mcg/mL, while 44 patients (79%) obtained trough levels below 10 mcg/mL despite the addition of nephrotoxic agents.
Orr, H., Trone, D., Elder, J., & Raj, A. (2017). Assessment of Initial Vancomycin Dosing in Pediatric Oncology Patients. Children, 4(9), 79. https://doi.org/10.3390/children4090079