Objective: The aim of this study is to investigate the association between leg-length-to-height ratio (LLHR) and metabolic syndrome (MetS) among Chinese children. Methods: 1236 children (619 obese and 617 nonobese children) aged 3-6. years participated in a cross-sectional survey in 2005 in Tianjin, China. Information on body adiposity, metabolic traits, and related covariates was obtained using a standardized protocol. LLHR was calculated as the ratio of leg length to stature. Results: In the multivariable logistic regression analyses, compared with those in the lowest quartile, odds ratios (OR) and 95% confidence intervals (CI) of MetS among children in the second through the highest quartiles of LLHR Z-score were 0.89 (95% CI, 0.64-1.25), 0.45 (95% CI, 0.32-0.63), and 0.37 (95% CI, 0.26-0.53), respectively, (P for trend<0.0001 across LLHR Z-score quartiles). Compared with children with both higher levels of LLHR and lower levels of adipose indices, the corresponding ORs of MetS for those with both lower levels of LLHR and higher levels of anthropometric indices were 4.51 (95% CI, 3.08-6.62) for BMI Z-score, 3.86 (95% CI, 2.60-5.73) for waist circumference, and 2.75 (95% CI, 1.85-4.10) for waist-to-hip ratio, respectively. Conclusions: Greater LLHR is inversely associated with MetS in Chinese children.
Liu, G., Liu, J., Li, N., Tang, Z., Lan, F., Pan, L., … Yu, Z. (2014). Association between leg length-to-height ratio and metabolic syndrome in Chinese children aged 3 to 6years. Preventive Medicine Reports, 1, 62–67. https://doi.org/10.1016/j.pmedr.2014.11.002