The Asthma Phenotype in the Obese: Distinct or Otherwise?

  • Farzan S
N/ACitations
Citations of this article
26Readers
Mendeley users who have this article in their library.

Abstract

Asthma is a heterogenous disorder that can be classified into several different phenotypes. Recent cluster analyses have identified an “obese-asthma” phenotype which is characterized by late onset, female predominance and lack of atopy. In addition, obesity among early-onset asthmatics clearly exists and heightens the clinical presentation. Observational studies have demonstrated that asthma among the obese has a clinical presentation that is more severe, harder to control, and is not as responsive to standard controller therapies. While weight loss studies have demonstrated improvement in asthma outcomes, further studies need to be performed. The current knowledge of the existence of two obesity-asthma phenotypes (early- versus late-onset asthma) should encourage investigators to study these entities separately since just as they have distinct presentations, their course, response to therapies, and weight loss strategies may be different as well.

Cite

CITATION STYLE

APA

Farzan, S. (2013). The Asthma Phenotype in the Obese: Distinct or Otherwise? Journal of Allergy, 2013, 1–8. https://doi.org/10.1155/2013/602908

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free