Autogenous Demineralized Dentin Graft for Third Molar Socket Regeneration - A Case Report

Abstract

The purpose of this case report is to evaluate the effects of a patient’s own demineralized dentin matrix (DDM) for socket preservation after extraction. A 27 year old male presented with slightly mesially inclined upper impacted right third molar with pericoronitis. Extraction of the impacted tooth was performed atraumatically and DDM granules were prepared from the extracted tooth. Firstly, the tooth was crushed by a newly developed auto-crush mill at 12,000 rpm for 60 seconds. The crushed granules were demineralized completely in 0.34 N nitric acid for 20 minutes and rinsed in distilled water. Immediate autograft of DDM was done into the tooth socket after 20 perforations into the socket surface. The results were evaluated clinically and radiographically at 3 and 12 months postoperatively. Dental X-ray just after the graft revealed radiopaque particles covering fully inside the socket. At 3 and 12 months of the follow-up, the socket appeared to be filled with uniform radiodense bone like tissue. The micro-CT and 3D micro-CT images at 12 months showed complete bone regeneration with no change in the vertical and horizontal dimension of the alveolar ridge. No significant difference was existed in radiodensity between new bone inside the socket and surrounding alveolar bone. The results of this case report suggest that autogenous DDM graft might be very effective as bone-forming materials for bone regeneration in the extracted socket.