Visual short-term memory of stimulus velocity in patients with unilateral posterior brain damage

Abstract

Neurophysiological studies indicate the existence of an area in the extrastriate monkey cortex specialized for the processing of stimulus motion. The present investigation was conducted to determine whether a homologous area exits in the human cortex that underlies the processing and short-term storage of velocity information. Contrast detection and velocity discrimination thresholds were measured in a group of 23 patients with unilateral focal damage to either the lateral occipital, temporal, or posterior parietal cortex. Their results were compared to those of 23 age- matched control subjects. Detection and discrimination thresholds were determined for spatially truncated sine-wave gratings presented 4° eccentric of fixation randomly in either the left and right visual fields. Contrast detection thresholds were measured in a spatial two-alternative forced- choice paradigm for three different drift rates (1, 2, and 4 Hz) for leftward and rightward drift directions. Simultaneous velocity discrimination thresholds were determined for reference and test gratings presented 4° left and right of fixation. Sequential velocity discrimination thresholds were measured using a delay, with a interstimulus interval (ISIs) of 1, 3, and 10 sec. In a subset of five patients with superior temporal lobe damage, spatial frequency discrimination thresholds for stationary gratings were also determined. The results indicate the following: (1) contrast detection thresholds for drifting gratings did not significantly differ between the patient and control groups; (2) velocity discrimination thresholds were significantly elevated in the patients; (3) velocity discrimination thresholds significantly increased with increasing ISI in the patients; (4) velocity discrimination thresholds were elevated most when the patients had a lesion in the superior temporal cortex; (5) in the subgroup of five patients with superior temporal lobe damage, spatial frequency discrimination thresholds were not significantly elevated. The results suggest that there is a visual area in the human posterior temporal cortex that is involved in the processing and short-term storage of the velocity of moving visual stimuli.