Carboxylic acids from Phyllanthus urinaria

Abstract

Five compounds, terephthalic acid mono-[2-(4-carboxy-phenoxycarbonyl)- vinyl] ester (1), (E)-3-(5′-hydroperoxy-2,2′-dihydroxy[1,1′- biphenyl]-4-yl)-2-propenoic acid (2), 3,4,5-trihydroxybenzoic acid (3), succinic acid (or butanedioic acid) (4), and 2,3,4,5,6-pentahydroxybenzoic acid (5), were isolated from Phyllanthus urinaria. The structures of these compounds were elucidated by means of spectral techniques including IR, MS, and 1D/2D NMR. 1 and 2 are new compounds. ©2005 Springer Science+Business Media, Inc.