A pharmacodynamic model for pancuronium

Abstract

Sir,-In the appendix to our recent paper we presented a series of formulae for the general solution of a three-compartment open model (equations 8-16). We regret that these equations contain a sign error, in that where the initial drug concentration C1(0) appears in these equations, it is entered as a positive quantity. It should be entered as a negative quantity. Those readers who wish to use these formulae (8-16) should therefore change C1(O) to - C1(O) in each instance. © 1979 Macmillan Journals Ltd.