A case of focal inferior limb sensory-motor status epilepticus as the only manifestation of a multiple sclerosis (MS) relapse is described. To obtain evidence of the relationship between the seizures, the cortical plaque and the left foot motor area, an EEG-fMRI co-registration study was undertaken demonstrating that seizure-related BOLD signal substantially overlapped with the inflammatory lesion involving the foot sensory-motor cortex. Seizures did not respond to intravenous anti-epileptic drugs (AEDs) but were controlled by steroid therapy. © 2010 British Epilepsy Association. Published by Elsevier Ltd. All rights reserved.
Gasparini, E., Benuzzi, F., Pugnaghi, M., Ariatti, A., Sola, P., Nichelli, P., & Meletti, S. (2010). Focal sensory-motor status epilepticus in multiple sclerosis due to a new cortical lesion. An EEG-fMRI co-registration study. Seizure, 19(8), 525–528. https://doi.org/10.1016/j.seizure.2010.06.015