Synthesis of novel chromenes as cytotoxic agents

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Abstract

Novel substituted chromenes, chromenopyrimidines and chromenotriazolopyrimidines were synthesised to explore their anticancer activity. Several compounds were evaluated for their antitumour activity, most of them revealed promising cytotoxic activity against breast cancer cell line MCF-7 in comparison to colchicine as positive control.

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Kandeel, M. M., Kamal, A. M., Abdelall, E. K. A., & Elshemy, H. A. H. (2013). Synthesis of novel chromenes as cytotoxic agents. Journal of Chemical Research, 37(2), 110–114. https://doi.org/10.3184/174751913X13573228322518

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