Pluripotent human stem cells: An overview

Abstract

For the past few years, cell therapy with pluripotent stem cells has been central to the prospect of regenerative medicine. From the traditional human embryonic stem cell (HSC) to the more recent induced pluripotent stem cells (iPSC), themain objective across all is to make use of the property of cell pluripotency to generate target cell types for therapeutic purposes. This chapter reviews some aspects of pluripotency in human cells, including its characteristics and regulatory factors, as well as various cell-reprogramming and single-cell analysis techniques developed for the manipulation of pluripotency in human cells and the clinical aspects of current methods.