A new cytotoxic 19-nor-cardenolide from the latex of antiaris toxicaria

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Abstract

A new nor-cardenolide, named toxicarioside H (1), was isolated from the latex of Antiaris toxicaria (Pers.) Lesch (Moraceae). Its structure was elucidated on the basis of HRFAB-MS and spectroscopic techniques (IR, UV, 1D and 2D NMR). Compound 1 showed significant cytotoxicity against K562, SGC-7901, SMMC-7721, and HeLa cell lines in vitro by MTT method. © 2009 by the authors.

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Dai, H. F., Gan, Y. J., Que, D. M., Wu, J., Wen, Z. C., & Mei, W. L. (2009). A new cytotoxic 19-nor-cardenolide from the latex of antiaris toxicaria. Molecules, 14(9), 3694–3699. https://doi.org/10.3390/molecules14093694

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