Roseocardin, a novel cardiotonic cyclodepsipeptide from Trichothecium roseum TT103

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Abstract

A new cyclodepsipeptide, designated roseocardin, was isolated from the culture broth of Trichothecium roseum TT103. Roseotoxin B and destruxins A and B were also isolated during the same procedure. The structure of roseocardin was determined by EI-MS, NMR and X-ray crystallographic analysis. Roseocardin as well as the other cyclodepsipeptides were shown to produce positive inotropic effects on rat heart muscles.

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APA

Tsunoo, A., Kamijo, M., Taketomo, N., Sato, Y., & Ajisaka, K. (1997). Roseocardin, a novel cardiotonic cyclodepsipeptide from Trichothecium roseum TT103. Journal of Antibiotics, 50(12), 1007–1013. https://doi.org/10.7164/antibiotics.50.1007

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