A new cyclodepsipeptide, designated roseocardin, was isolated from the culture broth of Trichothecium roseum TT103. Roseotoxin B and destruxins A and B were also isolated during the same procedure. The structure of roseocardin was determined by EI-MS, NMR and X-ray crystallographic analysis. Roseocardin as well as the other cyclodepsipeptides were shown to produce positive inotropic effects on rat heart muscles.
CITATION STYLE
Tsunoo, A., Kamijo, M., Taketomo, N., Sato, Y., & Ajisaka, K. (1997). Roseocardin, a novel cardiotonic cyclodepsipeptide from Trichothecium roseum TT103. Journal of Antibiotics, 50(12), 1007–1013. https://doi.org/10.7164/antibiotics.50.1007
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