Nanocrystalline hydroxyapatite: Micelle templated synthesis and characterization

Abstract

Nanocrystalline calcium phosphate based inorganic, hydroxyapatite (HAp), was synthesized using the dodecyl phosphate micelle system. The surfactant concentration during synthesis played an important role on the final properties of these HAp nanoparticles. A surfactant concentration close to the critical micelle concentration produced the nanoparticles with the highest surface area, with porous less agglomerated morphology. Compacts made of these nanopowders showed between 97 and 98% theoretical density of phase-pure HAp and promoted cell-material interaction when cytotoxicity tests were performed. © 2005 American Chemical Society.