Copper(I) bromide

Abstract

Li et al. developed a novel and efficient CC bond formation method via the CDC reaction of indoles and tetrahydroisoquinolines catalyzed by copper bromide in the presence of the oxidizing reagent TBHP. Figure persented Guo et al. described a mild and efficient tandem method for the synthesis of 2-aminobenzothiazoles. In the presence of CuBr and TBAB, a variety of 2-halobenzenamines underwent the tandem reaction with isothiocyanates in moderate to excellent yields. Figure persented The copper(I) bromide/1-(5,6,7,8-tetrahydroquinolin-8-yl)-2-methylpropan-1-one (CuBr/L3) combination catalyzed the crosscoupling reactions between aryl or heteroaryl halides and aqueous ammonia with high yields to produce primary aromatic or heteroaromatic amines at room temperature or under mild conditions. Figure persented Beletskaya et al. provided a catalytic version of the Sandmeyer bromination reaction employing a Cu(I)/Cu(II)/phen catalytic system. This synthetic protocol seems to be highly useful for the preparation of various aryl bromides and dibromides in excellent yields. Figure persented Zeitler et al. reported a new and efficient, atom-economic immobilization of various heterazolium salts, which could conveniently prepared via copper-catalyzed [3+2] cycloaddition. The high catalytic activity of their corresponding carbene derivatives was demonstrated in both intramolecular Stetter reactions and redox esterifications. Figure persented Chen et al. developed a copper-catalyzed three-component reaction of 2-ethynylaniline, sulfonyl azide, and nitroolefins. This reaction generates functionalized indoles in good yields and proceeds smoothly under mild conditions. Figure persented Nakamura et al. revealed a drastic skeletal rearrangement of readily accessible and fairly stable O-propargyl oximes to b-lactam derivatives catalyzed by copper bromide. The rearrangement is highly useful as an entirely new approach for synthesizing b-lactam derivatives in an efficient manner. Figure persented Lee et al. reported a Cu/bpy*-catalyzed method for the asymmetric insertion of (R)-diazocarbonyl compounds into the NH bonds of carbamates to generate an array of easily deprotected arylglycines in good enantiomeric excess. Figure persented Zhou et al. described a new method for the synthesis of benzofurans and indoles via CuBr-catalyzed couplingallenylation cyclization of terminal alkynes with N-tosylhydrazone derivatives. © Georg Thieme Verlag Stuttgart - New York.