The central nervous system (CNS) actions of several hormones, including insulin, regulate metabolism in the liver and other peripheral tissues. Inoue et al. (2006) have now identified an IL-6/STAT3-dependent pathway in the liver that mediates a portion of the hepatic metabolic response to CNS insulin. © 2006 Elsevier Inc.
Myers, M. G. (2006, April). Role reversal: Brain insulin and liver STAT3. Cell Metabolism. https://doi.org/10.1016/j.cmet.2006.03.003