Moraxella (Branhamella) catarrhalis BRO β-lactamase: A lipoprotein of gram-positive origin?

Abstract

In the past 20 years, BRO β-lactamase-producing Moraxella catarrhalis strains have emerged. We show that BRO is expressed as a 33-kDa lipoprotein associated with the inner leaflet of the outer membrane. To our knowledge, this is the first description of a lipidated β-lactamase in a gram-negative species.